The World Health Organization (WHO) estimated that the 2016 suicide rate was 10.6 suicides per 100,000 persons, with 80% of suicides occurring in low- and middle-income countries.² Across the six WHO regions, the incidence of suicide differed by a factor of 4 between the region with the highest rate (Europe) and the region with the lowest rate (the Eastern Mediterranean, including the Middle East). Explanations for this variation include differences in the classification of suicide, sociocultural attitudes toward suicide, access to lethal means of dying by suicide, and the adequacy of treatment for mental disorders. Worldwide, suicide rates vary according to age and sex, with the highest rates among older people and with higher rates among men (15.6 suicides per 100,000) than among women (7.0 per 100,000).² Suicide rates have been declining over recent decades in most of these regions, with an estimated 18% reduction from 2000 to 2016. The exception is the Americas; in the United States, rates have increased by 1.5% annually since 2000, and rates among men 45 to 64 years of age increased from 21 suicides per 100,000 in 1999 to 30 per 100,000 in 2017.